文章发表

Publications

Initial experience in a real-world Asian cohort with a circulating tumor DNA (ctDNA) mutation-based multi-cancer early detection (MCED) assay

Annals of Oncology, 2023

Complete mutation concordance with amplicon-based NGS between peripheral blood and bone marrow at 0.5% VAF threshold

American Association for Cancer Research, 2023

Amplicon-based liquid biopsy prospectively detects more tissue-confirmed guideline-recommended biomarkers in lung cancer

2023 World Conference on Lung Cancer

Development and evaluation of a multi-cancer screening (MCS) test for cancers common in Asia

Journal of Clinical Oncology, 2023

Combining plasma and tissue next-generation sequencing provides optimal treatment selection for metastatic NSCLC : a comparative study

Journal of Clinical Oncology, 2023

Liquid Biopsy in Combination with PET/CT Versus PET/CT alone in Diagnosis of Lung Cancer in Small Nodules

Journal of Clinical Oncology, 2023

Longitudinal tracking of ALK-positive lung cancer from plasma using circulating-tumor RNA and circulating-tumor DNA in the BRIGHTSTAR clinical trial

Journal of Clinical Oncology, 2023

Assessing the utility of liquid biopsy for determining actionable genetic mutations among indigenous Ghanaian women with metastatic Breast Cancer

Journal of Clinical Oncology, 2023

Liquid biopsy NGS test identifies actionable DNA mutations from CSF specimens of lung cancer patients

Annals of Oncology, 2022

A comprehensive next generation sequencing tissue assay for Asian-prevalent cancers—Analytical validation and performance evaluation with clinical samples

Frontiers in Medicine, 2022

Clinical Validation of a Promising New Amplicon-Based Liquid Biopsy Platform for Detection of Guideline Recommended Biomarkers in Metastatic NSCLC

Journal of Thoracic Oncology, 2022

Longitudinal Evaluation of Circulating Tumor DNA Using Sensitive Amplicon-Based Next-Generation Sequencing to Identify Resistance Mechanisms to Immune Checkpoint Inhibitors for Advanced Urothelial Carcinoma

The Oncologist, 2022

Peripheral T-Cell Receptor Repertoire Profiling in Non-small Cell Lung Cancer Using an Amplicon-Based Sequencing Assay

Journal of Thoracic Oncology, 2022

Retrospective Analysis of BRCA1/2 Alterations in Advanced NSCLC Using An Amplicon-based NGS Liquid Biopsy Assay

Journal of Thoracic Oncology, 2022

Sensitive Detection of Lung Cancer Using a Multiomic Plasma Cell-Free DNA Sequencing Assay

Journal of Thoracic Oncology, 2022

A cell-free RNA-based next-generation sequencing (NGS) assay for the detection of actionable gene fusions in patients with non–small cell lung cancer (NSCLC)

American Society of Clinical Oncology, 2022

Detection of homologous recombination deficiency (HRD) in cell-free DNA (cfDNA) using an amplicon-based next-generation sequencing (NGS) assay.

American Society of Clinical Oncology, 2022

Early detection of cancer using cell-free DNA (cfDNA) size analysis on a multiplexed amplicon-based next-generation sequencing (NGS) platform

American Society of Clinical Oncology, 2022

Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA

PLOS One, 2022

Complementing Tissue Testing With Plasma Mutation Profiling Improves Therapeutic Decision-Making for Patients With Lung Cancer

Frontiers in Medicine, 2022

Analytical and Clinical Validation of an Amplicon-based Next Generation Sequencing Assay for Ultrasensitive Detection of Circulating Tumor DNA

medRxiv, 2021

Complementing Tissue Testing with Plasma mutation Profiling Improves Therapeutic Decision Making for Lung Cancer Patients

medRxiv, 2021

Targeted ctDNA sequencing analysis reveals concurrent genomic alterations and its impact on TKI and immune checkpoint inhibitor therapy in advanced NSCLC from Asian population

American Society of Clinical Oncology, 2021

Comprehensive molecular profiling of advanced cancers in a real-world setting using an ultrasensitive amplicon-based next-generation sequencing (NGS) liquid biopsy assay

American Society of Clinical Oncology, 2021

Saliva is more sensitive than nasopharyngeal or nasal swabs for diagnosis of asymptomatic and mild COVID-19 infection

Scientific reports, 2021

A ‘Plasma-First’ Molecular Profiling Approach Complements Actionable Mutation Detection in Suspected Lung Cancer Patients

Journal of Thoracic Oncology, 2021

Clinical utility of a liquid biopsy diagnostic approach in lung cancer using amplicon-based next-generation sequencing in parallel with allele-specific PCR

American Society of Clinical Oncology, 2020

An ultrasensitive amplicon-based sequencing panel for noninvasive molecular testing of hematological malignancies using blood

American Society of Clinical Oncology, 2020

Detection of actionable gene mutations in breast cancer by amplicon-based next-generation sequencing liquid biopsy.

American Society of Clinical Oncology, 2020

A discrete choice experiment (DCE) study evaluating preferences of Asian adults for inherited cancer risk testing.

American Society of Clinical Oncology, 2020

A Viral Fragmentation Signature for SARS-CoV-2 in Clinical Samples Correlating with Contagiousness

Medrxiv, 2021

Validation of Saliva and Self-Administered Nasal Swabs for COVID-19 Testing

MDPI, 2020

Single Cell Hydrodynamic Stretching and Microsieve Filtration Reveal Genetic, Phenotypic and Treatment-Related Links to Cellular Deformability

Micromachines, 2020

Prognostic and predictive value of circulating tumour DNA (ctDNA) by amplicon-based next generation sequencing (NGS) of advanced pancreatic cancer (APC) in a phase I trial of oxaliplatin capecitabine and irinotecan (OXIRI) triplet chemotherapy.

Journal of Clinical Oncology, 2020

Ultrasensitive detection of diverse genomic alterations in hematological malignancies using a targeted amplicon-based sequencing approach

AACR, 2020

A multigene expression score for predicting response to anti-PD-1/PD-L1 therapy for clear cell renal cell cancer patients.

ASCO Genitourinary Cancers Symposium, 2019

Application of a comprehensive platform technology for detection of cancer-associated genomic alterations and viral DNA in liquid biopsies

Annals of Oncology, 2018

An enhanced next-generation sequencing liquid biopsy assay for simultaneous detection of somatic variants, microsatellite instability and viral DNA

Journal of Clinical Oncology, 2018

Automated Renal Cancer Grading Using Nuclear Pleomorphic Patterns

JCO Clinical Cancer Informatics, 2018

Evaluation of three polygenic risk score models for the prediction of breast cancer risk in Singapore Chinese

Oncotarget, 2018

The Issue of Tissue in Molecular Stratification

Oncologist, 2017

Identification of Novel Breast Cancer Risk Loci

Cancer Research, 2017

EGFR Mutation Detection in Plasma Cell-free DNA Correlates with Clinical Outcomes in Non-Small Cell Lung Cancer

Annals of Oncologist, 2017

Recognizing the Continuous Nature of Expression Heterogeneity and Clinical Outcomes in Clear Cell Renal Cell Carcinoma

Scientific Reports, 2017

Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care

Oncotarget,2017

Comparison of Circulating Tumour Cells and Circulating Cell-Free Epstein-Barr Virus DNA in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy

Scientific Reports, 2016

Tumor-derived circulating endothelial cell clusters in colorectal cancer

Science Translational Medicine, 2016

A five-gene reverse transcription-PCR assay for pre-operative classification of breast fibroepithelial lesions

Breast Cancer Research, 2016

A Multigene Assay Identifying Distinct Prognostic Subtypes of Clear Cell Renal Cell Carcinoma with Differential Response to Tyrosine Kinase Inhibition

European Oncology, 2015